2019-08-20 03:21:05
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.师资队伍.
  姓名王永强   性别:男   民族:汉
  部门:有机化学与化学生物学学部 
  籍贯:甘肃天水   职称:教授
  邮箱:wangyq@nwu.edu.cn   电话:    029-88305966(O)
研究方向: 1.高效合成新策略、新方法的开发; 2.高活性天然产物全合成;3.药物及功能分子设计与合成
简    介
王永强,理学博士,教授,博士生导师。1997年6月获兰州大学应用化学专业学士学位;2000年6月获兰州大学有机化学硕士学位;2003年6月获兰州大学有机化学院博士学位;2003–2005 香港科技大学研究助理;2005–2007 美国Brandeis University博士后;2007–2009中山大学化学与化学工程学院副教授;2009–现在 西北大学化学与材料科学学院教授。2010年入选“教育部新世纪优秀人才支持计划”,2011年入选陕西省特聘专家。先后主持四项国家自然科学基金;一项陕西省自然科学基金;一项陕西省教育厅自然科学基金;一项中国科学院天然产物有机合成化学重点实验室研究基金。作为学术骨干参与多项国家、省部级项目。近年来在国际顶尖专业期刊J. Am. Chem. Soc., Angew. Chem. Int. Ed., Org. Lett., Adv. Synth. Catal.等上发表多篇学术论文,论文引用次数已达600余次。

主要从事高效合成新策略、新方法的开发,高活性的天然产物分子的全合成,新药及功能分子的设计与合成方面的研究工作。

主要代表性论文:

34. Shi-Huan Guo, Xing-Long Zhang, Gao-Fei Pan, Xue-Qing Zhu, Ya-Ru Gao, and Yong-Qiang Wang*, Synthesis of Difluoromethylthioesters from Aldehydes, Angew. Chem. Int. Ed. 2018, 57, 1663-1667.
33. Chen-Hao Ru, Shi-Huan Guo, Gao-Fei Pan, Xue-Qing Zhu, Ya-Ru Gao, and Yong-Qiang Wang*, Synthesis of Hydrazines via Radical Generation and Addition of Azocarboxylic tert-Butyl Esters, Org. Lett. 2018, 20, 1910-1913.
32. Da-Yu Wang, Shi-Huan Guo, Gao-Fei Pan, Xue-Qing Zhu, Ya-Ru Gao, and Yong-Qiang Wang*, Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups, Org. Lett. 2018, 20, 1794-1797.
31. Gao‐Fei Pan Xue‐Qing Zhu Rui‐Li Guo Ya‐Ru Gao Yong‐Qiang Wang*, Synthesis of Enones and Enals via Dehydrogenation of Saturated Ketones and Aldehydes, Adv. Synth. Catal. 2018, 360,4774-4783.
30. Shi-Huan Guo, Meng-Yue Wang, Gao-Fei Pan, Xue-Qing Zhu, Ya-Ru Gao, Yong-Qiang Wang*, Synthesis of Monofluoromethylthioesters from Aldehydes, Adv. Synth. Catal. 2018, 360, 1861-1869.
29. Ya-Ru Gao, Da-Yu, Wang, Yong-Qiang Wang*, Asymmetric Syntheses of Amaryllidaceae Alkaloids (-)-Crinane and (+)-4a-Dehydroxycrinamabine, Org. Lett. 2017, 19, 3516-3519.
28. Dong-Dong Guo, Bin Li, Da-Yu Wang, Ya-Ru Gao, Shi-Huan Guo, Gao-Fei Pan, Yong-Qiang Wang*, Synthesis of 6H‑Benzo[c]chromenes via Palladium-Catalyzed Intramolecular Dehydrogenative Coupling of Two Aryl C-H Bonds, Org. Lett. 2017, 19, 798-801.
27. Li Su, Dong-Dong Guo, Bin Li, Shi-Huan Guo, Gao-Fei Pan, Ya-Ru Gao, Yong-Qiang Wang*, Palladium-Catalyzed Direct Monoarylation of Aryl C-H Bond with Iodoarenes, ChemCatChem 2017, 9, 2001-2008.
26. Bin Li, Dong-Dong Guo, Shi-Huan Guo, Gao-Fei Pan, Ya-Ru Gao, Yong-Qiang Wang*, Palladium-Catalyzed C-H Functionalization of Phenyl 2-Pyridylsulfonates, Chem. Asian J. 2017, 12, 130144.
25. Xue-Qing Zhu, Shuai Mao, Dong-Dong Guo, Bin Li, Shi-Huan Guo, Ya-Ru Gao, Yong-Qiang Wang*, Copper-Catalyzed Isomerization and Cyclization of E/Z-oHaloaryl N-Sulfonylhydrazones: Convenient Access to 1HIndazoles, ChemCatChem 2017, 9, 1084-1091.
24.Gao-Fei Pan, Li Su, Yan-Lei Zhang, Shi-Huan Guo, Yong-Qiang Wang*, Organocatalytic one-pot asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones, RSC Adv. 2016, 6, 25375-25378.
23. Shuai Mao, Xue-Qing Zhu, Ya-Ru Gao, Dong-Dong Guo, Yong-Qiang Wang*, Silver-Catalyzed Coupling of Two C(sp3)-H Groups and One-Pot Synthesis of Tetrasubstituted Furans, Thiophenes, and Pyrroles, Chem. Eur. J. 2015, 21, 11335-11339 (hot paper).
22. Shuai Mao, Ya-Ru Gao, Xue-Qing Zhu, Dong-Dong Guo, Yong-Qiang Wang*, Copper-Catalyzed Radical Reaction of N‑Tosylhydrazones: Stereoselective Synthesis of (E)‑Vinyl Sulfones, Org. Lett. 2015, 17, 1692-1695.
21. Shuai Mao, Ya-Ru Gao, Shao-Liang Zhang, Dong-Dong Guo, Yong-Qiang Wang*, Copper(II)-Promoted CC Bond Formation by Oxidative Coupling of Two C(sp3)H Bonds Adjacent to Carbonyl Group to Construct 1,4-Diketones and Tetrasubstituted Furans, Eur. J. Org. Chem. 2015, 876-885.
20. Dong Yang, Shuai Mao, Ya-Ru Gao, Dong-Dong Guo, Shi-Huan Guo, Bin Li, Yong-Qiang Wang*, Palladium-catalyzed C-7 alkenylation of indolines using molecular oxygen as the sole oxidant, RSC Adv. 2015, 5, 23727-23736.
19. Jing-Wen Yu, Shuai Mao, Yong-Qiang Wang*, Copper-catalyzed base-accelerated direct oxidation of CH bond to synthesize benzils, isatins, and quinoxalines with molecular oxygen as terminal oxidant, Tetrahedron Lett. 2015, 56, 1575-1580.
18. Na-Na Li, Yan-Lei Zhang, Shuai Mao, Ya-Ru Gao, Dong-Dong Guo, and Yong-Qiang Wang*, Palladium-Catalyzed CH Homocoupling of Furans and Thiophenes Using Oxygen as the Oxidant, Org. Lett. 2014, 16, 2732-2735.
17. Shi-Huan Guo, Sheng-Zhu Xing, Shuai Mao, Ya-Ru Gao, Wen-Liang Chen, Yong-Qiang Wang, Oxa-Michael addition promoted by the aqueous sodium carbonate, Tetrahedron Lett. 2014, 55, 6718–6720.
16. Yan-Lei Zhang, Yong-Qiang Wang*, Enantioselective biomimetic cyclization of 2′-hydroxychalcones to flavanones, Tetrahedron Lett. 2014, 55, 3255-3258.
15.Yu-Fei Wang, Ya-Ru Gao, Shuai Mao, Yan-Lei Zhang, Dong-Dong Guo, Zhao-Lei Yan, Shi-Huan Guo, and Yong-Qiang Wang*, Wacker-Type Oxidation and Dehydrogenation of Terminal Olefins Using Molecular Oxygen as the Sole Oxidant without Adding Ligand, Org. Lett. 2014, 16, 1610-1613.
14. Zhao-Lei Yan, Wen-Liang Chen, Ya-Ru Gao, Shuai Mao, Yan-Lei Zhang and Yong-Qiang Wang*, Palladium-Catalyzed Intermolecular C2 Alkenylation of Indoles Using Oxygen as the Oxidant, Adv. Synth. Catal. 2014, 356, 1085-1092.
13. Jian Zhang, Yong-Qiang Wang, Xin-Wei Wang, and Wei-Dong Z. Li, Transannular Reductive Rearrangement of α‑Amino Ketones: Construction of Aza-tricyclic Frameworks of Several Alkaloids, J. Org. Chem. 2013, 78, 6154-6162.
12.Ya-Ru Gao, Shi-Huan Guo, Zhuan-Xiang Zhang, Shuai Mao, Yan-Lei Zhang, Yong-Qiang Wang*, Concise synthesis of (+)-serinolamide A, Tetrahedron Lett. 2013, 54, 65116513.
11. Xiao-Ji Tang, Zhao-Lei Yan, Wen-Liang Chen, Ya-Ru Gao, Shuai Mao, Yan-Lei Zhang, Yong-Qiang Wang*, Aza-Michael reaction promoted by aqueous sodium carbonate solution, Tetrahedron Lett. 2013, 54, 26692673.
10. Wen-Liang Chen, Ya-Ru Gao, Shuai Mao, Yan-Lei Zhang, Yu-Fei Wang, Yong-Qiang Wang*, Palladium-Catalyzed Intermolecular C3 Alkenylation of Indoles Using Oxygen as the Oxidant, Org. Lett. 2012, 14, 5920-5923.
9. Shao-Liang Zhang, Zhao-Feng Xue, Ya-Ru Gao, Shuai Mao, Yong-Qiang Wang*. Triple condensation of aryl methyl ketones catalyzed by amine and trifluoroacetic acid: straightforward access to 1,3,5-triarylbenzenes under mild conditions, Tetrahedron Lett. 2012, 53, 2428-2431.
8. Yi Wang, Hongming Li, Yong-Qiang Wang, Yan Liu, Bruce M. Foxman, Li Deng*, Asymmetric Diels-Alder Reactions of 2-Pyrones with a Bifunctional Organic Catalyst. J. Am. Chem. Soc. 2007, 129, 6364-6365.
7. Yong-Qiang Wang, Jun Song, Ran Hong, Hongming Li, Li Deng*, Asymmetric Frield-Crafts Reaction of Indoles with Imines by an Organic Catalyst. J. Am. Chem. Soc. 2006, 128, 8156-8157.
6. Hongming Li, Yong-Qaing Wang, Li Deng*. Enantioselective Friedel-Crafts Reaction of Indoles with Carbonyl Compounds Catalyzed by Bifunctional Cinchona Alkaloids. Org. Lett. 2006, 8, 4063-4065.
5. Yan Zhang, Yongqiang Wang, Wei-Min Dai*. Efficient Remote Axial-to-Central Chirality Transfer in Enantioselective SmI2-Mediated Reductive Coupling of Aldehydes with Crotonates of Atropisomeric 1-Naphthamides. J. Org. Chem. 2006, 71, 2445-2455.
4. Bao-Chun Ma, Yong-Qiang Wang, Wei-Dong Z. Li*, An Alternative Synthesis of Dolby-Weinreb Enamine en Route to Cephalotaxine. J. Org. Chem. 2005, 70, 4528-4530.
3. Wei-Min Dai*, Kelly Ka Yim Yeung, Yong-qiang Wang, The First Example of Atropisomeric Amide-Derived P, O-Ligands Used for an Asymmetric Heck Reaction. Tetrahedron 2004, 60, 4425-4430.
2. Wei-Dong Z. Li*, Yong-Qiang Wang, A Novel and Efficient Total Synthesis of Cephalotaxine. Org. lett. 2003, 5, 2931-2934.
1. Yongqiang Wang, Wenfei Tan, Weidong Z. Li, Yulin Li*. A Facile Synthetic Approach to Prenylated Flavanones: First Total Syntheses of (±)-Bonannione A and (±)-Sophoraflavanone A. J. Nat. Prod. 2001, 196-199.

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