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有机化学与化学生物学学部

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书记信箱:
chemdzz@nwu.edu.cn

院长信箱:
chemdir@nwu.edu.cn

 
 
.师资队伍.
  姓名杨小峰   性别:男   民族:汉
  部门:分析化学学部    出生年月:1973年3月
  籍贯:陕西 西安   职称:教授
  邮箱:xfyang@nwu.edu.cn
研究方向: 主要从事荧光传感与分子识别、生物分析化学及化学发光分析等方面的研究工作。
简    介
  杨小峰,博士、教授、博导。2002年7月于厦门大学化学化工学院分析化学专业毕业获得博士学位,2002年9月进入西北大学化学博士后流动站工作,2004年出站后留校任教。其中2010年8月至2011年8月在美国波特兰州立大学从事访问学者工作。目前主要从事分子发光分析研究,研究课题涉及荧光传感与分子识别、荧光探针的设计合成,化学发光分析、生化分析等。目前主要致力于研究与发展高灵敏与高选择性的荧光传感体系,不断提高方法的灵敏度、准确度和选择性,以解决在生命科学、环境科学等领域的科学研究中所面临的分析化学问题。目前主持国家自然科学基金面上项目2项,陕西省自然科学基金1项,陕西教育厅专项科研计划项目1项,横向项目1项。近年先后在Angew.Chem.Int.Ed.,Anal.Chem.,Chem.Sci.、Chem.Commun.等SCI源期刊共发表学术论文20余篇。2007年获陕西省科学技术奖一等奖(第六名),2010年获陕西省高等学校科学技术奖一等奖(第一名)。2017年入选陕西省中青年科技创新领军人才支持计划。

  近年发表的代表性论文:

  1) Tianyi Cheng,Wenming Huang,Di Gao,Zhe Yang,Congjie Zhang,Haixia Zhang,Jianjian Zhang,Hua Li,and Xiao-Feng Yang*, Anal.Chem.2019,91,10894−10900.

  2) Jiangjiang Sun,Qin Wang,Jiajun Yang,Jianjian Zhang,Zheng Li,Hua Li,Xiao-Feng Yang,Xiao-Feng Yang*, 2,4-Dinitrobenzenesulfonate-functionalized carbon dots as aturn-on fluorescent probe for imaging of biothiols in living cells,Microchimica Acta,2019,186,402.

  3) Haihua Chen,Xueyun Gong,Xiawei Liu,Zheng Li,Jianjian Zhang,Xiao-Feng Yang*,A nitroso-based fluorogenic probe for rapid detection of hydrogen sulfide in living cells,Sensors and Actuators B:Chemical,2019,281,542-548.

  4) Biliu Wu,Jiajun Yang,Jianjian Zhang,Zheng Li,Hua Li,Xiao-Feng Yang*,A ratiometric fluorescent probe for the detection of endogenous hydroxyl radicals in living cells,Talanta,2019,196,317–324.

  5) Yuan Liu,Dandan Ren,Jianjian Zhang,Hua Li,Xiao-Feng Yang*,A fluorescent probe for hydrazine based on anewly developed 1-indanone-fused coumarin scaffold,Dyes and Pigments,2019,162,112-119.

  6)Shengrui Zhang,Qin Wang,Xiawei Liu,Jianjian Zhang,Xiao-Feng Yang*,Zheng Li,Hua Li*,Sensitive and Selective Fluorescent Probe for Selenol in Living Cells Designed via apKa Shift Strategy,Anal.Chem.,2018,90,4119−4125.

  7)Shengrui Zhang,Guojun Chen,Yuanyuan Wang,Qin Wang,Yaogang Zhong,Xiao-Feng Yang,*Zheng Li,Hua Li*,Far-Red Fluorescent Probe for Imaging of Vicinal Dithiol-Containing Proteins in Living Cells Based on apKa Shift Mechanism,Anal.Chem.,2018,90,2946-2953.

  8)Dandan Ren,Yuan Liu,Xiawei Liu,Zheng Li,Hua Li,Xiao-Feng Yang*,Spirohydrazine rhodamine as afluorescent chemodosimeter for the selective detection of Cu(II)ions and its application in live cell imaging,Sensors and Actuators B,2018,255,2321–2328.

  9)Xin Wang,Xiaogang Liu,Tianyi Cheng,Hua Li,Xiao-Feng Yang*,Development of 4-hydrazinyl-7-nitrobenzofurazan as afluorogenic probe for detecting malondialdehyde in biological samples,Sensors and Actuators B,2018,254,248–254.

  10)Qin Wang,Shengrui Zhang,Yaogang Zhong,Xiao-Feng Yang*,Zheng Li,and Hua Li*,Preparation of Yellow-Green-Emissive Carbon Dots and Their Application in Constructing aFluorescent Turn-On Nanoprobe for Imaging of Selenol in Living Cells,Anal.Chem.,2017,89,1734−1741.

  11)Yuanyuan Wang,Yaogang Zhong,Qin Wang,Xiao-Feng Yang*,Zheng Li,Hua Li*,Ratiometric Fluorescent Probe for Vicinal Dithiol-Containing Proteins in Living Cells Designed via Modulating the Intramolecular Charge Transfer−Twisted Intramolecular Charge Transfer Conversion Process,Anal.Chem.,2016,88,10237−10244.

  12)Xueyun Gong,Xiao-Feng Yang,*Yaogang Zhong,Haihua Chen,Zheng Li,A flavylium-based turn-on fluorescent probe for imaging hydrogen polysulfides in living cells,RSC Adv.,2016,6,88519–88525.

  13)Yuanyuan Wang,Xiao-Feng Yang,*Yaogang Zhong,Xueyun Gong,Zheng Li,Hua Li,*Development of ared fluorescent light-up probe for highly selective and sensitive detection of vicinal dithiol-containing proteins in living cells,Chemi.Sci.,2016,7,518-524.

  14)Yuan Hou,Xiao-Feng Yang,*Yaogang Zhong,Zheng Li,Development of fluorescent probes for hydrogen polysulfides byusing cinnamate ester as the recognition unit,Sensors and Actuators B:Chemical,2016,232,531–537.

  15)Xueyun Gong,Xiao-Feng Yang*,Yaogang Zhong,Yanhong Chen,Zheng Li,A mitochondria-targetable near-infrared fluorescent probe for imaging nitroxyl(HNO)in living cells,Dyes and Pigments,2016,131,24-32.

  16)Linhua Geng,Xiao-Feng Yang,*Yaogang Zhong,Zheng Li,Hua Li,“Quinon-ephenol”transduction activated excited-state intramolecular proton transfer:A new strategy toward ratiometric fluorescent probe for sulfite in living cells,Dyes and Pigments,2015,120,213-219.

  17)Yu-Wei Duan,Xiao-Feng Yang,*Yaogang Zhong,Yuan Guo,*Zheng Li,Hua Li,A ratiometric fluorescent probe for gasotransmitter hydrogen sulfide based on acoumarin-benzopyrylium platform,Anal.Chim.Acta,2015,859,59–65.

  18)Yanhong Chen,Xin Wang,Xiao-Feng Yang,*Yaogang Zhong,Zheng Li,Hua Li Development of aratiometric fluorescent probe for sulfite based on acoumarin–benzopyrylium platform,Sens.Actuat.B.,2015,206,268–275.

  19)Xiao-Feng Yang,*Qian Huang,Yaogang Zhong,Zheng Li,Hua Li,*Mark Lowry,Jorge O.Escobedo,Robert M.Strongin*,A dual emission fluorescent probe enables simultaneous detection of glutathione and cysteine/homocysteine,Chem.Sci.,2014,5(6),2177-2183.

  20)Hongmin Lv,Xiao-Feng Yang*,Yaogang Zhong,Yuan Guo*,Zheng Li,Hua Li,Native Chemical Ligation Combined with Spirocyclization of Benzopyrylium Dyes for the Ratiometric and Selective Fluorescence Detection of Cysteine and Homocysteine,Anal.Chem.,2014,86,1800-1807.

  21)Xiaofeng Yang*,Yixing Guo,Robert M.Strongin*,Conjugate addition/cyclization sequence enables selective and simultaneous fluorescence detection of cysteine and homocysteine,Angew.Chem.Int.Ed.,2011,50,10690-10693.

  22)Hui Wen,Qian Huang,Xiao-Feng Yang*,Spirolactamized benzothiazole-substituted N,N-diethylrhodol:a new platform to construct ratiometric fluorescent probes.Chem.Commun.,2013,49,4956-4958.

  

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化学与材料科学学院 地址:陕西省西安郭杜教育产业园区学府大道1号 电话:029-81535026 邮件:chembgs@nwu.edu.cn